2nd International Conference on
Renaissance London Heathrow Hotel, UK
Genetic Mapping is the process of determining the location and order of genes or genetic markers on chromosomes. It provides insights into inheritance patterns, identifies disease-associated genes, and facilitates molecular genetics research. There are several types of genetic maps: linkage maps, based on recombination frequencies where closely linked genes are inherited together; physical maps, which measure actual distances in base pairs between genes or markers; and comparative maps, which compare genomes across species to identify conserved regions. Methods of genetic mapping include pedigree analysis, which studies inheritance in families; recombination analysis, estimating gene distances via crossover events; and the use of molecular markers such as microsatellites, SNPs, and RFLPs for high-resolution mapping. Modern approaches like genome-wide association studies (GWAS) allow identification of genes linked to traits or diseases across large populations. Applications of genetic mapping include locating disease-causing genes, assisting in marker-based therapies, understanding human evolution and population genetics, and identifying candidate genes for functional studies. Overall, genetic mapping is a foundational tool in human genetics, critical for research, diagnostics, and advancing personalized medicine.
