Human Genetics

Genetic Susceptibility to Human Obesity involves inherited genetic factors that influence the likelihood of becoming obese. While lifestyle choices like diet and exercise are important, genetics play a significant role in fat storage, appetite regulation, and energy processing. Key genes linked to obesity include the FTO gene, which is associated with increased appetite, the MC4R gene, which affects appetite and energy balance, and leptin and its receptors, which regulate energy. Genetic variations interact with environmental factors like diet and physical activity, contributing to obesity risk, highlighting the complex relationship between genetics and lifestyle in obesity development.