Human Genetics

Immunogenetics is the study of how genetic variations influence the immune system's response to pathogens and its role in immune-related diseases. It focuses on key concepts like the Major Histocompatibility Complex (MHC), which helps the immune system recognize pathogens. The diversity of HLA genes affects susceptibility to autoimmune diseases, infections, and cancers. Genetic factors also shape immune responses to environmental triggers, influencing conditions such as allergies and immunodeficiencies. Immunogenetics is crucial in organ transplantation, vaccine efficacy, and personalized medicine, helping optimize treatments based on genetic predispositions and improving outcomes for immune-related disorders.