Pharmacogenetics

Pharmacogenetics is the study of how an individual’s genetic makeup affects their response to drugs, influencing factors such as efficacy, metabolism, and susceptibility to adverse effects. Variations in genes encoding drug-metabolizing enzymes, transporters, and drug targets can cause significant differences in how patients absorb, distribute, metabolize, and eliminate medications. Understanding these genetic influences enables personalized medicine, where drug selection and dosing are tailored to an individual’s genetic profile, improving therapeutic outcomes and minimizing side effects. Pharmacogenetics has wide-ranging applications in oncology, psychiatry, cardiology, and other medical fields, guiding treatment strategies for conditions including cancer, depression, and cardiovascular disorders. Advances in genomic sequencing, bioinformatics, and high-throughput screening have facilitated the identification of clinically relevant genetic variants, enhancing the precision of drug therapy. By integrating genetic insights into clinical decision-making, pharmacogenetics continues to revolutionize healthcare, contributing to safer, more effective, and individualized treatments, and shaping the future of precision medicine.

  • Pharmacogenomics
  • Developments of Pharmacogenomics
  • Pharmacodynamics
  • Genetic Factors in Drug Effects