Rare Diseases and Orphan Drugs

This mosaicism is occurred when the two or more genomes in the body of an individual from a single zygote and the mosaicism from chimerism and the condition in which an individual has two different, and complete genomes in her or his body that are from zygotes. These diseases arise through a new mutation occurs after fertilization that is postzygotic mutations. they have been described in the recent years and the cause of many different disorders many of these are neurocutaneous diseases .in some case or disorders, there is a genetic predisposition to the development of tumors.

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