Chromatography & Mass Spectrometry


Chromatography is a method used for separating organic and inorganic compounds so that they can be analyzed and studied by scientists. Chromatography is the great physical method for observing mixtures and solvents. Chromatography is used to determine the presence of cocaine in urine, alcohol in blood, PCB's in fish, and lead in water. There are four main types of chromatography. They are Liquid Chromatography, Gas Chromatography, Thin-Layer Chromatography and Paper Chromatography.

The technique studies the effect of ionizing energy on molecules. LC-MS is an analytical technique that combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry.