Bio-pharmaceutics is the interaction of both physical and chemical properties of the drug, the dosage form in which the drug is given, and the route of administration on the rate and extent of systemic drug absorption. Bio-Pharmaceutics plays a very important role in drug discovery like drug disposition, Innovations in clinical development, Pharmaceutical technology, Pharmaceutical analysis, and drug delivery, Drug style, Targeted drug, Sustained drug delivery system, Routes of administration, elementary drug development.