Huntington’s disease


Huntington’s disease is inherited from Parents and often symptoms will be more like Parkinson’s disease which include problem with mood, mental abilities, Swallowing, Speaking, Sleep Disturbances followed by loss of co-ordination and unsteady gait. Mutation to gene called HTT(Huntingtin) may cause disturbances in the brain and results in death of brain cell and leads to Huntington’s disease. Abnormalities with the mutant huntingtin include Cardiac Failure, Weight Loss, Osteoporosis, reduced glucose level. This condition is normally observed in the individuals under the age of fifties. The normal huntingtin gene includes 17 to 20 repetitions of this code among total of more than 3,100 codes.The defect that causes Huntington's disease includes 40 or more repeats. Genetic tests for Huntington's disease measure the number of repeats present in an individual's huntingtin protein gene.The huntingtin gene defect involves extra repeats of one specific chemical code in one small section of chromosome 4.

  • Cognitive Behavioural Therapy
  • Transcriptional Dysregulation
  • Neuronal Replacement
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