Cancer and Oncology Research

Cancer genetics and epigenetics study how genetic mutations and epigenetic modifications drive cancer. Genetic changes, like mutations in oncogenes and tumor suppressor genes, alter cell behavior, leading to uncontrolled growth. Epigenetic modifications, such as DNA methylation and histone changes, affect gene expression without altering DNA sequences, potentially silencing tumor-suppressing genes or activating oncogenes. Together, these insights help identify biomarkers for early detection and personalized treatments, with therapies now targeting both genetic mutations and epigenetic changes to improve cancer outcomes.